Fatty liver disease: feeling tired, weak or losing weight could indicate a risk


Fatty liver disease is a common condition caused by the storage of extra fat in the liver. Most people don’t have any symptoms and it doesn’t cause them serious problems. In some cases, however, this can lead to liver damage.

Classic symptoms of liver disease include nausea, vomiting, right upper quadrant abdominal pain, and jaundice (a yellowing of the skin due to high levels of bilirubin in the bloodstream), Medicine Net said.

The health site added, “Fatigue, weakness and weight loss can also occur.

“The liver is responsible for many critical functions in the body and if it is sick or injured, the loss of these functions can cause significant damage to the body.”

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Fatigue and weakness

Fatigue is a symptom commonly described by people with liver disease (hepatitis), whether the hepatitis is caused by a virus, excessive alcohol or fat consumption, or an inherited disease, the GI Society said. .

He added, “The associated fatigue can be intermittent or constant, mild or debilitating.

“There is no relationship between the severity of liver disease and the severity of fatigue.

“Those with minimal liver disease may experience total exhaustion while those with severe liver disease may not feel tired at all, or vice versa.”

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In a study published in the US National Library of Medicine, National Institutes of Health, fatigue and weakness in liver disease were analyzed in more detail.

Fatigue is the most common symptom reported by patients with liver disease, according to the study.

“Although the underlying pathogenesis of fatigue in liver disease is still unclear, it appears to involve changes in central neurotransmission, which result from signaling between the diseased liver and the brain,” the study noted. .

He continued, “A better understanding of the neurotransmitter pathways and systems involved may provide specific therapies directed against fatigue associated with liver disease.

“Although the exact prevalence of fatigue in patients with chronic liver disease is somewhat variable in different studies and with different specific liver diseases, it is evident that fatigue is the most common complaint among this group of patients. . ”


Unexplained weight loss is a noticeable drop in body weight that occurs even if the person is not trying to lose weight.

Unexplained weight loss can be a symptom of a serious illness.

Weight loss does not happen because of changes in diet, exercise, or lifestyle.

Weight loss of 10 pounds or more, or five percent of body weight, over a period of six to 12 months is considered unexplained.

Causes of fatty liver disease

Some people get fatty liver disease without any pre-existing conditions.

However, these risk factors make you more likely to develop it:

Being obese or overweight

Have type 2 diabetes or insulin resistance

Have a metabolic syndrome such as insulin resistance, high blood pressure, high cholesterol, and high triglyceride levels

Take certain prescription drugs.


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